Immune Checkpoint Inhibitors in Cancer Immunotherapy
Tofacitinib for Refractory Immune-Related Colitis from PD-1 Therapy
N Engl J Med 2020
A case description of the successful use of tofacitinib in a patient with gastric cancer receiving pembrolizumab whose… Read More
Checking in with immune checkpoint inhibitors: Results of a needs assessment survey of Canadian rheumatologists
J Cancer Sci Therap 2019
Objectives: Immune checkpoint inhibitors (ICI) are associated with immune-related adverse events (irAE), including autoimmune rheumatologic diseases. The Canadian Research… Read More
Immune-related Adverse Events Associated with Cancer Immunotherapy: A Review for the Practicing Rheumatologist
J Rheum 2019
Immune checkpoint inhibitors have revolutionized cancer therapy by blocking inhibitory pathways of the immune system to fight cancer cells. Their use… Read More
Hydroxychloroquine is a safe and effective steroid-sparing agent for immune checkpoint inhibitor-induced inflammatory arthritis
Clin Rheumatol 2019
Immunotherapy for cancer treatment continues to evolve, and immune checkpoints have proven successful therapeutic targets. With success has come the challenge… Read More
Immune Checkpoint Inhibitor Associated Rheumatic Adverse Events: a Review of Their Presentations and Treatments
Curr Treat Options in Rheum 2019
Purpose of review: Immune checkpoint inhibitors (ICI) are now the cornerstone of treatment for metastatic melanoma and are… Read More
Hepatitis is the new myositis: immune checkpoint inhibitor-induced myositis
Melanoma Res 2018
This article describes two cases of myositis associated with immune checkpoint inhibitor therapy for melanoma, in which both diagnoses were delayed… Read More
Adverse events associated with immune checkpoint inhibitor treatment for cancer
CMAJ 2019
Inhibitors against cytotoxic T-lymphocyte--associated protein 4 and programmed cell death 1 immune checkpoints are novel agents that modulate immune pathways and enhance… Read More
Rheumatic Immune-related Adverse Events Associated with Immune Checkpoint Inhibitors for Cancer: Coming soon to a clinic near you.
CRAJ 2018
An overview of rheumatologic immune-related adverse events associated with immune checkpoint inhibitors, along with a case description of inflammatory polyarthritis developing after… Read More